10^th World Kidney Congress

Mineral and Bone Disorder in CKD

In individuals with chronic kidney disease, mineral and bone disorders, collectively known as renal osteodystrophy, are prevalent. Patients with chronic kidney diseases often exhibit imbalances in calcium and phosphorus levels in their blood due to hormonal disruptions, ultimately leading to kidney failure and the need for dialysis. The kidneys play a crucial role in preserving healthy bone mass and structure by regulating phosphorus and calcium levels in the bloodstream. Healthy kidneys stimulate the conversion of a type of vitamin D, obtained from food, into calcitriol, the active form of the vitamin. Calcitriol aids the kidneys in maintaining blood calcium levels and promoting bone formation. Additionally, the kidneys eliminate excess phosphorus, ensuring a balance between phosphorus and calcium levels in the blood. Maintaining optimal phosphorus levels in the blood is essential for preserving strong and healthy bones.